NitroAccelerator does not work with SQL Server protocol encryption enabled. Encrypted data does not compress well, so NitroAccelerator will just bypass and not compress any encrypted packets it encounters. Because of this you will not see any benefit with NitroAccelerator until the protocol encryption is turned off. However, NitroAccelerator includes its own option for protocol encryption, which is done after the data is already compressed. This maintains the performance benefit while still securing your connection.